| MPC | Minor Planets Circular | - | Atmospheric Research Center |
| MPC | Maximum Permissible Concentration | - | Computer Acronyms(common) |
| MPC | Model Predictive Control | - | Computer Acronyms(common) |
| MPC | Matchbox PC | - | Human Genome |
| MPC | Multimedia Personal Computer | - | Human Genome |
| MPC | Manual Pointing Controller | - | Organizations |
| MPC | Memory Protection Check | - | Organizations |
| MPC | Meteorological Prediction Center | - | Organizations |
| MPC | Mid Power Controller | - | Organizations |
| MPC | Midbody Pyro Controller | - | Organizations |
| MPC | Minor Planet Center - Minor Planet Circular | - | Astronomy |
| MPC | Mother-of-pearl Clouds | - | Business and Finance |
