| SD | Std. Deviation | - | Computer Acronyms(common) |
| SD | Secure Digital | - | Computer and Internet |
| SD | Scaling And DisPlay | - | Organizations |
| SD | Smoke Detector | - | Organizations |
| SD | Space Division (AFSC) | - | Organizations |
| SD | Space Division (Rockwell) | - | Organizations |
| SD | Spare DisPosition | - | Organizations |
| SD | Specification Document | - | Organizations |
| SD | LSoftware Development Laboratory | - | Organizations |
| SD | LStandard Distribution List | - | Organizations |
| SD | Sheriff's Department - Smoke/Decontamination-South Dakota (postal Symbol) - Sudan (ISO 3166 Digram) | - | Astronomy |
| SD | Sindhi Language (ISO 639-1 Code) | - | Astronomy |
| SD | Standard Deviation | - | Business and Finance |
