| SPA | Scintillation-proximity Assay | - | Computer Acronyms(common) |
| SPA | Self-consistent Phonon Approximation | - | Computer Acronyms(common) |
| SPA | Separated Pair Approxn. (wave Function) | - | Computer Acronyms(common) |
| SPA | Shielded-potential Approxn. (in Electronic Structure) | - | Computer Acronyms(common) |
| SPA | S-Band Power Amplifier | - | Organizations |
| SPA | Servo Power Amplifier | - | Organizations |
| SPA | Shared Peripheral Area | - | Organizations |
| SPA | Signal Processor Assembly | - | Organizations |
| SPA | Signal Processor Assembly | - | Organizations |
| SPA | Space Processing Application | - | Organizations |
| SPA | Steering Position Amplifier | - | Organizations |
| SPA | Spanish Language (ISO 639-2 Code) | - | Astronomy |