| S-HIS | Scanning High Resolution Interferometer Sounder | - | Scuba Diving |
| SAB | Satellite Applications Branch (old. NESDIS) | - | Scuba Diving |
| SAFIRE | Spectroscopy Of The Atmosphere Using Far InfraRed Emission | - | Scuba Diving |
| SAGE | Stratospheric Aerosol And Gas Experiment (EOS) | - | Scuba Diving |
| SBUV | Solar Backscatter UltraViolet Radiometer (EOS) | - | Scuba Diving |
| SDS | Satellite Data Services | - | Scuba Diving |
| SHARP | Summer High School Apprenticeship Research Program (NASA) | - | Scuba Diving |
| SSEC | Space Science And Engineering Center | - | Scuba Diving |
| SSU | Stratospheric Sounding Unit (TOVS) | - | Scuba Diving |
| STEP | Satellite Technology Education Program (WSGC) | - | Scuba Diving |
| SWAMP | Science Working Group For The AM Platform (EOS) | - | Scuba Diving |