| L | Launch | - | Organizations |
| L | Left | - | Organizations |
| L | Length | - | Organizations |
| L | Level | - | Organizations |
| L | Low | - | Organizations |
| L | Lumen | - | Organizations |
| L&C | Laboratory And Checkout | - | Organizations |
| L&D | Landing And Deceleration | - | Organizations |
| L&L | Launch And Landing | - | Organizations |
| L&S | Logistics And SuPport | - | Organizations |
| L&T | Laboratory And Test | - | Organizations |
| L-BAND | S-Band 390 To 1550 MHz | - | Organizations |
| L-L | Line-to-Line | - | Organizations |
| L-P | Low Pressure | - | Organizations |
| L/D | Length-to-Diameter | - | Organizations |
| L/D | Lift-to-Drag (Ratio) | - | Organizations |
| L/H | Local Horizontal | - | Organizations |
| L/O | Lift-off | - | Organizations |
| L/S | Landing Site | - | Organizations |
| L/S | LLoad SYstem | - | Organizations |
| L/T | Load Test | - | Organizations |
| L02 | Liquid Oxygen | - | Organizations |
| LA | Lanthanum | - | Organizations |
| LA | Launch Abort | - | Organizations |
| LA | Launch Aft | - | Organizations |
| LA | Launch Area | - | Organizations |
| LA | Launch Azimuth | - | Organizations |
| LA | Lightning Arrester | - | Organizations |
| LA | Low Attitude | - | Organizations |
| LAAD | Los Angeles Aircraft Division (Rockwell) | - | Organizations |
| LACB | Landing Aids Control Building (SLF At KSC) | - | Organizations |
| LACIE | Large Area Crop Inventory Experiment | - | Organizations |
| LACIP | Large Area Crop Inventory Program | - | Organizations |
| LAGEOS | Laser Geodynamic Satellite | - | Organizations |
| LAGS | Launch Abort Guide Simulation | - | Organizations |
| LAIR | Liquid Air | - | Organizations |
| LAIU | Launch Abort Interface Unit | - | Organizations |
| LAN | Local Area Network | - | Organizations |
| LANDC | Instrumentation And Communication | - | Organizations |
| LAPS | Left Aft Propulsion System (Subsystem) | - | Organizations |
| LARC | Langley Research Center (Hampton | - | Organizations |
| LARS | Laminar Angular Rate Sensor | - | Organizations |
| LARSSYAA | For Aircraft Analysis | - | Organizations |
| LARSSYAA | Laboratory For Application Of Remote Sensing System | - | Organizations |
| LASCOT | Large Screen Color Television System | - | Organizations |
| LASV | Low Altitude Supersonic Vehicle | - | Organizations |
| LAT | Large Angle Torque | - | Organizations |
| LAT | Latch | - | Organizations |
| LAT | Lateral | - | Organizations |
| LAT | Latitude | - | Organizations |
| LAT | Lot Acceptance Test | - | Organizations |
| LATS | LDEF Assembly And Transportation System | - | Organizations |
| LB | Launch Boost | - | Organizations |
| LB | Launch Bus | - | Organizations |
| LB | Load Bank | - | Organizations |
| LB | Low Bay | - | Organizations |
| LB | Lower Brace | - | Organizations |
| LB | Pound | - | Organizations |
| LBDT | Low Bay Dolly Tug | - | Organizations |
| LBK | Left Bank | - | Organizations |
| LBL | Left Buttock Line | - | Organizations |
| LBM | Load Buffer Memory | - | Organizations |
| LBNPD | Lower Body Negative Pressure Device | - | Organizations |
| LBR | Low Bit Rate | - | Organizations |
| LC | Incremental Cost | - | Organizations |
| LC | Information Center | - | Organizations |
| LC | Initial Condition | - | Organizations |
| LC | Integrated Circuit | - | Organizations |
| LC | Intercom (Orbiter To Ground Via Hardline) | - | Organizations |
| LC | Intercommunications | - | Organizations |
| LC | Intercomputer | - | Organizations |
| LC | Interim Change | - | Organizations |
| LC | Internal Combustion | - | Organizations |
| LC | Ion Chamber | - | Organizations |
| LC | LaunchCountdown | - | Organizations |
| LC | Launch Complex | - | Organizations |
| LC | Launch Critical | - | Organizations |
| LC | Left Center | - | Organizations |
| LCA | Launch Control Amplifier | - | Organizations |
| LCA | Load Controller (Control) Assembly | - | Organizations |
| LCA | Load Controller Assembly | - | Organizations |
| LCB | Least Common Bit | - | Organizations |
| LCC | Launch Commit Criteria | - | Organizations |
| LCC | Launch Control Center | - | Organizations |
| LCC | Launch Control Center (KSC) | - | Organizations |
| LCC | Life Cycle Cost | - | Organizations |
| LCCD | Launch Commit Criteria Document | - | Organizations |
| LCD | LaunchCountdown | - | Organizations |
| LCF | LowCycle Fatigue | - | Organizations |
| LCG | Liquid Cooled Garment | - | Organizations |
| LCG | Liquid-cooled Garment | - | Organizations |
| LCH | Latch | - | Organizations |
| LCH | LatLaunch | - | Organizations |
| LCHTF | LowCYcle High Temperature Fatigue | - | Organizations |
| LCL | Local | - | Organizations |
| LCM | Least Common Multiple | - | Organizations |
| LCMS | LowCost Modular Spacecraft | - | Organizations |
| LCO | MMCUniform Central Number | - | Organizations |
| LCOM | Logic Control OutPut Module | - | Organizations |
| LCR | LowCross Range | - | Organizations |
