| E | Epsilon | - | Business and Finance |
| E-MAIL | Electronic Mail | - | Business and Finance |
| EAA | Export Administration Act | - | Business and Finance |
| EAC | Employee Activities Committee | - | Business and Finance |
| EAC | Estimated Cost At Completion | - | Business and Finance |
| EACR | Environmental Area Characterization Report | - | Business and Finance |
| EAD | Energy And Air Division (EPA | - | Business and Finance |
| EAG | Environmental Assessments Group | - | Business and Finance |
| EAG | Exposure Assessment Group | - | Business and Finance |
| EAO | Economy Act Order | - | Business and Finance |
| EAR | Ethics Advisory Review | - | Business and Finance |
| EAR | Export Administration Regulations | - | Business and Finance |
| EARN | European Academic Research Network | - | Business and Finance |
| EASDS | Earth Science And Applications Data System | - | Business and Finance |
| EASOE | European Arctic Stratospheric Ozone Experiment | - | Business and Finance |
| EBAM | Electron-beam-accessed-memory | - | Business and Finance |
| EBB | Equivalent Blockbody | - | Business and Finance |
| EBCDIC | Extended Binary-coded Decimal Interchange Code | - | Business and Finance |
| EBR-II | Experimental Breeder Reactor II | - | Business and Finance |
| EBUFR | Enhanced Binary Universal Form | - | Business and Finance |
| EC | European Community | - | Business and Finance |
| ECA | Earth-crossing Asteroids | - | Business and Finance |
| ECAO | Environmental Criteria And Assessment Office | - | Business and Finance |
| ECCN | Export Control Classification Number | - | Business and Finance |
| ECG | Environmental Coordinating Group | - | Business and Finance |
| ECHAM4 | European Center HAMburg 4 | - | Business and Finance |
| ECMOP | Experimental Center For Mesoscale Ocean Predictions | - | Business and Finance |
| ECMRWF | European Centre For Medium-Range Weather Forecasts | - | Business and Finance |
| ECMWF | European Centre For Medium-range Weather Forecasting | - | Business and Finance |
| ECN | Energy Research Foundation | - | Business and Finance |
| ECOD | Export Control Operations Division | - | Business and Finance |
| ECP | Engineering Change Proposal | - | Business and Finance |
| ECR | Economic Cleanup Responsibility Act | - | Business and Finance |
| ECR | Engineering Change Request | - | Business and Finance |
| ECS | EOSDIS Core System | - | Business and Finance |
| ECSA | Early Career Scientists Assembly | - | Business and Finance |
| ECTD | Emission Control Technology Division | - | Business and Finance |
| ECU | Environmental Crimes Unit | - | Business and Finance |
| EDA | Ecosystem Dynamics And The Atmosphere | - | Business and Finance |
| EDAS | Ecosystem Dynamics And The Atmosphere Section | - | Business and Finance |
| EDC | EROS Data Center | - | Business and Finance |
| EDF | Exploratory Development Facility | - | Business and Finance |
| EDF/ DER | Electricit? De France/ Direccion Des Etudes Et Recherche | - | Business and Finance |
| EDMS | Electra Data Management System | - | Business and Finance |
| EDP | Electronic Data Processing | - | Business and Finance |
| EDP | Embedded Data Processor | - | Business and Finance |
| EDRS | European Data Relay Satellite | - | Business and Finance |
| EDS | Environmental Data Service | - | Business and Finance |
| EDS | Electronic Data Systems | - | Business and Finance |
| EDUCOM | A Consortium Of Industrial Organizations And University Computing Administrators | - | Business and Finance |
| EEA | European Environment Agency | - | Business and Finance |
| EEC | European Economic Community | - | Business and Finance |
| EECF | Earthnet ERS-1 Central Facility | - | Business and Finance |
| EED | Exposure Evaluation Division | - | Business and Finance |
| EEI | Edison Electric Institute | - | Business and Finance |
| EEID | EOSDIS External Interface Document | - | Business and Finance |
| EEMD/NV | Engineering And Energy Management | - | Business and Finance |
| EEMOC | European EMOC | - | Business and Finance |
| EEOC | Equal Employment Opportunity Commission | - | Business and Finance |
| EEPROM | Electronically Eraseable And Programmable Read Only Memory | - | Business and Finance |
| EERL | Eastern Environmental Radiation Lab | - | Business and Finance |
| EERU | Environmental Emergency Response Unit | - | Business and Finance |
| EES | Earth & Environmental Science | - | Business and Finance |
| EESI | Environment & Energy Study Institute | - | Business and Finance |
| EETFC | Environmental Effects | - | Business and Finance |
| EEZSCAN | Exclusive Economic Zone Scan | - | Business and Finance |
| EF | Error Function | - | Business and Finance |
| EF | Emission Factor | - | Business and Finance |
| EFC | Experimental Forecast Center | - | Business and Finance |
| EFEDA | European Field Experiment In Desertification-Threatened Area | - | Business and Finance |
| EFF | Experimental Forecast Facility | - | Business and Finance |
| EFI | Enrico Fermi Institute | - | Business and Finance |
| EFNS | Educational Foundation For Nuclear Science | - | Business and Finance |
| EFT | Enhanced Forecaster Tools | - | Business and Finance |
| EFTA | European Free Trade Association | - | Business and Finance |
| EFTC | European Fluorocarbon Technical Committee | - | Business and Finance |
| EG&G | Inc. | - | Business and Finance |
| EGA | Enhanced Graphics Adapter | - | Business and Finance |
| EGD | Effluent Guidelines Division | - | Business and Finance |
| EGP | Exterior Gateway Protocol | - | Business and Finance |
| EGS | European Geophysical Society | - | Business and Finance |
| EGSE | Electronic Ground Support Equipment | - | Business and Finance |
| EGTF | Electron Gun Test Facility | - | Business and Finance |
| EH | Oxidation Potential | - | Business and Finance |
| EH | Assistant Secretary For Environment | - | Business and Finance |
| EHF | Extremely High Frequency | - | Business and Finance |
| EHF | Extremely High Frequency | - | Business and Finance |
| EI | Electron Ionization | - | Business and Finance |
| EIA | Energy Information Administration | - | Business and Finance |
| EIA | Electronic Industries Association | - | Business and Finance |
| EIB | Environmental Improvement Board | - | Business and Finance |
| EIC | Earth Information System | - | Business and Finance |
| EICC | Emergency Information Control Center | - | Business and Finance |
| EINET | Enterprise Integration Network | - | Business and Finance |
| EIR | Eidgenossisches Institut Fur Reaktorforschung | - | Business and Finance |
| EIS | Environmental Impact Statement | - | Business and Finance |
| EISA | Extended Industry Standard Architecture | - | Business and Finance |
| EISCAT | European Incoherent Scatter Radar System | - | Business and Finance |
| EISPACK | Eigensystem Package Subroutine Computing Facility | - | Business and Finance |
| EL NI-O | The Little Boy | - | Business and Finance |
