| S&B | Salary And Benefits | - | Business and Finance |
| S&R | Search And Rescue | - | Business and Finance |
| S&R | Search And Rescue | - | Business and Finance |
| S&T | Science And Technology | - | Business and Finance |
| S-POL | S-band Dual Polarization Doppler Radar | - | Business and Finance |
| S/N | Signal-to-noise Ratio | - | Business and Finance |
| S/TM | Stratospheric/tropospheric Measurements | - | Business and Finance |
| SABL | Scanning Aerosol Backscatter Lidar | - | Business and Finance |
| SAC | Strategic Air Command | - | Business and Finance |
| SAC | Science Advisory Committee | - | Business and Finance |
| SAC-C | Argentina's Scientific Applications Satellite | - | Business and Finance |
| SADCC | South African Development Coordination Conference | - | Business and Finance |
| SAFARI | Southern African Fire-Atmospheric Research Initiative | - | Business and Finance |
| SAFARI-2000 | The Southern African Regional Science Initiative | - | Business and Finance |
| SAFE | A Proposed Australian Savanna Fire Experiment | - | Business and Finance |
| SAGE | Stratospheric Aerosol And Gas Experiment | - | Business and Finance |
| SAI | Sudden Auroral Intensity | - | Business and Finance |
| SAIC | Science Applications International Corporation | - | Business and Finance |
| SAM | Subsynoptic Advection Model | - | Business and Finance |
| SAM | Sun-angle Magnetometer | - | Business and Finance |
| SAM | Stratospheric Aerosol Measurement | - | Business and Finance |
| SAM I | Sensing With Active Microwaves | - | Business and Finance |
| SAMS | Stratospheric And Mesospheric Sounder | - | Business and Finance |
| SAO | Surface Airways Observation | - | Business and Finance |
| SAO | Semiannual Oscillation | - | Business and Finance |
| SAR | Synthetic Aperture Radar | - | Business and Finance |
| SAR | Subcommittee On Atmospheric Research | - | Business and Finance |
| SAR-C | SAR-C Band | - | Business and Finance |
| SAR-X | SAR-X Band | - | Business and Finance |
| SARSAT | Search And Rescue Satellite-Aided Tracking | - | Business and Finance |
| SAS | Small Astronomy Satellite | - | Business and Finance |
| SAS | Statistical Analysis System | - | Business and Finance |
| SAV | State-of-the-atmosphere Variable | - | Business and Finance |
| SAVE | Stratospheric Aerosol Validation Experiment | - | Business and Finance |
| SAVE | South Atlantic Ventilation Experiment | - | Business and Finance |
| SAWRS | Supplementary Aviation Weather Reporting System | - | Business and Finance |
| SBF | Scientific Balloon Facility | - | Business and Finance |
| SBIR | Small Business Innovative Research | - | Business and Finance |
| SBUV | Solar Backscatter Ultrav Iolet | - | Business and Finance |
| SC | Subtropical Stratocumulus | - | Business and Finance |
| SCAMS | Scanning Microwave Spectrometer | - | Business and Finance |
| SCAR | Scientific Committee For Antarctic Research | - | Business and Finance |
| SCAR | Special Committee For Antarctic Research | - | Business and Finance |
| SCARAB | Scanner For Radiation Budget | - | Business and Finance |
| SCATE | Sulfur Chemistry In The Antarctic Troposphere Experiment | - | Business and Finance |
| SCATT | Scatterometer | - | Business and Finance |
| SCCCAMP | South Central Coast Cooperative Aerometric Monitoring Program | - | Business and Finance |
| SCCM | Single-column CCM | - | Business and Finance |
| SCD | Scientific Computing Division | - | Business and Finance |
| SCDUG | Scientific Computing Division Users Group Scelming | - | Business and Finance |
| SCEP | Study Of Critical Environmental Problems | - | Business and Finance |
| SCF | Standard Cubic Feet | - | Business and Finance |
| SCGB | Special Committee For The Geosphere-Biosphere | - | Business and Finance |
| SCM | Stratospheric Circulation Model | - | Business and Finance |
| SCM | Small Core Memory | - | Business and Finance |
| SCM | Solar Constant Monitor | - | Business and Finance |
| SCMS | Software Configuration Management Section | - | Business and Finance |
| SCO | Subcarrier Oscillators | - | Business and Finance |
| SCOPE | Scientific Committee On Problems Of The Environment | - | Business and Finance |
| SCOR | Scientific Committee For Oceanographic Research | - | Business and Finance |
| SCOSTEP | Scientific Committee On Solar-Terrestrial Physics | - | Business and Finance |
| SCPP | Sierra Cooperative Pilot Project | - | Business and Finance |
| SCR | Selective Chopper Radiometer | - | Business and Finance |
| SCR | Silicon Controlled Rectifier | - | Business and Finance |
| SCS | Soil Conservation Service | - | Business and Finance |
| SCSC | Summer Computer Simulation Conferences | - | Business and Finance |
| SCSI | Small Computer System Interface | - | Business and Finance |
| SCST | State Committee On Science & Technology | - | Business and Finance |
| SCST | State Committee On Science & Technology | - | Business and Finance |
| SD | Standard Deviation | - | Business and Finance |
| SDAM | Satellite Data Access And Management Format | - | Business and Finance |
| SDBE | Shear-Directed Balloon Experiment | - | Business and Finance |
| SDD | Systems Development Division | - | Business and Finance |
| SDF | Shared Data Facility | - | Business and Finance |
| SDHS | Satellite Data Handling System | - | Business and Finance |
| SDM | Suit Of Software For UNIX-based Computing Platforms | - | Business and Finance |
| SDM | Scientific Data Management | - | Business and Finance |
| SDS | Solar Disk Sextant | - | Business and Finance |
| SDS | Scientific Data Systems | - | Business and Finance |
| SDSC | San Diego Supercomputing Center | - | Business and Finance |
| SDSD | Satellite Data Services Division | - | Business and Finance |
| SDSMT | South Dakota School Of Mines & Technology | - | Business and Finance |
| SDVR | Single-Doppler Velocity Retrieval | - | Business and Finance |
| SEAB | Secretary Of Energy Advisory Board | - | Business and Finance |
| SEAC | (National Bureau Of) Standards Eastern Automatic Computer | - | Business and Finance |
| SEAD | Secretary Of Energy Advisory Board | - | Business and Finance |
| SEASAT | Sea Satellite | - | Business and Finance |
| SEAWIFS | Sea Wide-Field Sensor | - | Business and Finance |
| SEC | Securities & Exchange Commission | - | Business and Finance |
| SEC | Science Executive Committee | - | Business and Finance |
| SEDI | Structure Of The Earth's Deep Interior | - | Business and Finance |
| SEDI | Structure Of The Earth's Deep Interior | - | Business and Finance |
| SEE | Solar EUV Experiment | - | Business and Finance |
| SEL | Space Environment Laboratory | - | Business and Finance |
| SEM | Scanning Electron Microscope | - | Business and Finance |
| SEM | Space Environment Monitor | - | Business and Finance |
| SEM | System Element Management | - | Business and Finance |
| SEQUAL | Seasonal Equatorial Atlantic Study | - | Business and Finance |
| SERI | Solar Energy Research Institute | - | Business and Finance |
| SERON | Southeastern Regional Oxidant Network Program | - | Business and Finance |
