| F | Fahrenheit | - | Business and Finance |
| F | Femto | - | Business and Finance |
| F | Frequency | - | Business and Finance |
| F | Forad | - | Business and Finance |
| F&A | Finance And Administration | - | Business and Finance |
| F-V | Fussell-Vesely | - | Business and Finance |
| F/P-INT | Fabry-Perot Interferometer | - | Business and Finance |
| F/P-INT | Fabry Perot Interferometer | - | Business and Finance |
| F77 | FORTRAN77 | - | Business and Finance |
| FAA | Federal Aviation Administration | - | Business and Finance |
| FAC | Facilities Advisory Council | - | Business and Finance |
| FAC | Friday Afternoon Club | - | Business and Finance |
| FACA | Federal Advisory Committee Act | - | Business and Finance |
| FACE | Florida Area Cirrus Experiment | - | Business and Finance |
| FACE | Also Known As FACE '75 | - | Business and Finance |
| FAGS | Federation Of Astronomical And Geophysical Services | - | Business and Finance |
| FAL | Frontier Airline | - | Business and Finance |
| FAME | Florida Area Mesoscale Experiment | - | Business and Finance |
| FAME | Formatting And Multiplexing Equipment | - | Business and Finance |
| FAN | File Array Notation | - | Business and Finance |
| FAO | Food And Agriculture Organization | - | Business and Finance |
| FAPS | Fate Of Atmospheric Pollutants Study | - | Business and Finance |
| FAPS | Freedom Attached Payloads | - | Business and Finance |
| FAQ | Frequently Asked Questions | - | Business and Finance |
| FAS | Federation Of American Scientists | - | Business and Finance |
| FASB | Financial Accounting Standards Board | - | Business and Finance |
| FASCODE | Fast Atmosphere Signature Code | - | Business and Finance |
| FASE | Foundation For Advancement In Science And Education | - | Business and Finance |
| FASINEX | Frontal Air-Sea Interaction Experiment | - | Business and Finance |
| FASTEX | Fronts Atlantic Storm Track Experiment | - | Business and Finance |
| FAT | Factory Acceptance Test | - | Business and Finance |
| FATS | Factory Acceptance Test Specification | - | Business and Finance |
| FATS | Firearms Training Simulator | - | Business and Finance |
| FATS | FORTRAN Automatic Timing System | - | Business and Finance |
| FATS | Forward Area Target Surveillance System | - | Business and Finance |
| FATS | South African Air Force Tactical Support Command | - | Business and Finance |
| FB | Blanketing Frequency | - | Business and Finance |
| FB | Funds Budgeted | - | Business and Finance |
| FB | Fleischmann Building | - | Business and Finance |
| FBA | Forecasting By Analogy | - | Business and Finance |
| FBI | Federal Bureau Of Investigation | - | Business and Finance |
| FCA | Functional Configuration Audit | - | Business and Finance |
| FCC | Federal Communications Commission | - | Business and Finance |
| FCCSET | Federal Coordinating Council On Science | - | Business and Finance |
| FCM | Federal Coordinator For Meteorological Services And Supporting Research | - | Business and Finance |
| FCOM | Federal Coordinators Office Of Meteorology | - | Business and Finance |
| FCST | Federal Council For Science And Technology | - | Business and Finance |
| FD | Facility Division | - | Business and Finance |
| FDA | Food And Drug Administration | - | Business and Finance |
| FDC | Fluid Dynamics Conference | - | Business and Finance |
| FDCA | Federal Drug And Cosmetics Act | - | Business and Finance |
| FDDA | Fiber Distributed Data Interface | - | Business and Finance |
| FDDI | Fiber-distributed Data Interface | - | Business and Finance |
| FDF | Flight Dynamics Facility | - | Business and Finance |
| FDM | Full-depth Model | - | Business and Finance |
| FDMA | Frequency Division Multiple Access | - | Business and Finance |
| FDT | Fully Developed Turbulence | - | Business and Finance |
| FE | Front-end | - | Business and Finance |
| FEMA | Federal Emergency Management Agency | - | Business and Finance |
| FEOSH | Federal Employee Occupational Safety And Health | - | Business and Finance |
| FEP | Front End Processor | - | Business and Finance |
| FEPCA | Federal Environmental Pesticides Control Act | - | Business and Finance |
| FEPCA | Federal Environmental Pollution Control Act | - | Business and Finance |
| FERC | Federal Energy Regulatory Commission | - | Business and Finance |
| FERMILAB | FERMI National Acceleration Laboratory | - | Business and Finance |
| FEST | Fronts Experiment Systems Test | - | Business and Finance |
| FET | Field-effect Transistor | - | Business and Finance |
| FEWS | Follow-on Early Warning System | - | Business and Finance |
| FFDCA | Federal Food, Drug, And Cosmetic Act (US) | - | Business and Finance |
| FFP | Firm Fixed Price | - | Business and Finance |
| FFRDCS | Federally Funded Research And Development Centers | - | Business and Finance |
| FFS | Flight Facilities Survey | - | Business and Finance |
| FFT | Fast Fourier Transform | - | Business and Finance |
| FFTF | Fast Flux Test Facility | - | Business and Finance |
| FFTS | Fast-Fourier Transforms | - | Business and Finance |
| FGCMS | Fast GC / MS = Fast Gas Chromatography / Mass Spectrometry | - | Business and Finance |
| FGGE | First GARP Global Experiment | - | Business and Finance |
| FHSA | Federal Hazardous Substances Act | - | Business and Finance |
| FHWA | Federal Highway Administration | - | Business and Finance |
| FIAR | European Aviation Partnership | - | Business and Finance |
| FICA | Federal Insurance Contributions Act | - | Business and Finance |
| FICS | Facility Information And Control System | - | Business and Finance |
| FIFE | First ISLSCP Field Experiment | - | Business and Finance |
| FIFE II | First ISLSCP Field Experiment II | - | Business and Finance |
| FIFOLIB | N/A | - | Business and Finance |
| FIFRA | Federal Insecticide | - | Business and Finance |
| FILOS | Far Infrared Limb Observing Spectrometer | - | Business and Finance |
| FIPS | Federal Information Processing Standard | - | Business and Finance |
| FIRE | First ISLSCP Regional Experiment | - | Business and Finance |
| FIRE | First ISCCP Radiation Experiment | - | Business and Finance |
| FIRE | Fast Imaging Ranicon Experiment | - | Business and Finance |
| FIRE-ACE | First ISCCP International Satellite Cloud Climatology Program | - | Business and Finance |
| FIRS | Fourier Transform Infrared Sounder | - | Business and Finance |
| FIS | Financial Information System | - | Business and Finance |
| FIVRS | Financial Information Variance Reporting System | - | Business and Finance |
| FL | Foothills Laboratory | - | Business and Finance |
| FL1 | First Flight Model | - | Business and Finance |
| FL2 | Second Flight Model | - | Business and Finance |
| FLAGE | Flexible Lightweight Agile Guided Experiment | - | Business and Finance |
| FLAT | Full Look At Turbulent Kinetic Energy | - | Business and Finance |
