| DAC | Delayed Action Command | - | Atmospheric Research Center |
| DACS | DATA Acquisition And Control Subsystem | - | Atmospheric Research Center |
| DAO | Dominion Astrophysical Observatory | - | Atmospheric Research Center |
| DARA | Deutsche Agentur Fuer Raumfahrtangelegenheiten | - | Atmospheric Research Center |
| DARPA | Defense Advanced Research Projects Agency | - | Atmospheric Research Center |
| DC | Delta Clipper | - | Atmospheric Research Center |
| DCA | Defense Communications Agency | - | Atmospheric Research Center |
| DCCS | Dynamic Cell Culture System | - | Atmospheric Research Center |
| DCX | Delta Clipper EXperimental | - | Atmospheric Research Center |
| DDCU | DC-to-DC Converter Unit | - | Atmospheric Research Center |
| DDTE | Design | - | Atmospheric Research Center |
| DEC | Declination | - | Atmospheric Research Center |
| DESAT | Desaturation | - | Atmospheric Research Center |
| DFRC | Dryden Flight Research Center | - | Atmospheric Research Center |
| DFRF | Dryden Flight Research Facility | - | Atmospheric Research Center |
| DIRBE | Diffuse Infrared Background Experiment | - | Atmospheric Research Center |
| DLR | Deutsche Forschungsanstalt Fuer Luft- Und Raumfahrt | - | Atmospheric Research Center |
| DM | Dark Matter | - | Atmospheric Research Center |
| DMR | Differential Microwave Radiometer | - | Atmospheric Research Center |
| DMSP | Defense Meteorological Satellite Program | - | Atmospheric Research Center |
| DOD | Department Of Defense | - | Atmospheric Research Center |
| DOE | Department Of Energy | - | Atmospheric Research Center |
| DOE | Department Of Education | - | Atmospheric Research Center |
| DOE | Department Of The Environment | - | Atmospheric Research Center |
| DOMSAT | Domestic Satellite | - | Atmospheric Research Center |
| DOR | Differenced One-way Range | - | Atmospheric Research Center |
| DOT | Department Of Transportation | - | Atmospheric Research Center |
| DPM | Drop Physics Module | - | Atmospheric Research Center |
| DPSS | DATA Processing Services Subsystem | - | Atmospheric Research Center |
| DRAO | Dominion Radio Astrophysical Observatory | - | Atmospheric Research Center |
| DRSS | DATA Relay Satellite System | - | Atmospheric Research Center |
| DSCS | Defense Satellite Communications System | - | Atmospheric Research Center |
| DSN | Deep Space Network | - | Atmospheric Research Center |
| DSO | Detailed Supplementary Objective | - | Atmospheric Research Center |
| DSP | Defense Support Program | - | Atmospheric Research Center |
| DSS | Deep Space Station | - | Atmospheric Research Center |
| DSSC | Deep Space Station Complex | - | Atmospheric Research Center |
