| B-ISDN | Broadband-Integrated Services Digital Network | - | Human Genome |
| B2B | Business-to-Business | - | Human Genome |
| BAPI | Business Application Programming Interface | - | Human Genome |
| BASIC | Beginners All-purpose Symbolic Instruction Code | - | Human Genome |
| BAT | Bandwidth Allocation Technology | - | Human Genome |
| BBS | Bulletin Board System | - | Human Genome |
| BCC | Blind Carbon Copy | - | Human Genome |
| BCC | Block Check Character | - | Human Genome |
| BCD | Binary Coded Decimal | - | Human Genome |
| BDP | Bandwidth-delay Product | - | Human Genome |
| BEDO RAM | Burst EDO RAM | - | Human Genome |
| BEOS | Be, Inc. Operating System | - | Human Genome |
| BG | Big Grin | - | Human Genome |
| BGA | Ball-grid Array | - | Human Genome |
| BGP | Border Gateway Protocol | - | Human Genome |
| BICMOS | Bipolar Complementary Metal Oxide Semiconductor | - | Human Genome |
| BIOS | Basic Input/Output System | - | Human Genome |
| BIT | Binary Digit | - | Human Genome |
| BITNET | Because Its Time Network | - | Human Genome |
| BLOB | Binary Large Object | - | Human Genome |
| BNC | Bayonet Neill Concelman | - | Human Genome |
| BOOTP | BOOTstrap Protocol | - | Human Genome |
| BPEL | Business Process Execution Language | - | Human Genome |
| BPL | Bits Per Line | - | Human Genome |
| BPP | Bits Per Pixel | - | Human Genome |
| BPS | Bits Per Second | - | Human Genome |
| BRI | Basic-Rate Interface | - | Human Genome |
| BSC | Base Station Controller | - | Human Genome |
| BSD | Berkeley Software (System) Distribution (Design) | - | Human Genome |
| BSML | Biosequence Markup Language | - | Human Genome |
| BSWD | BellSouth Intelligent Wireless Data Network | - | Human Genome |
| BTW | By The Way | - | Human Genome |
| B8ZS | binary, 8 zero substitution line code
| - | Human Genome |
| BBAA | broad band access arrangement
| - | Human Genome |
| BBAS | Broadband Access Services
| - | Human Genome |
| BBKUP&R | backup and restore
| - | Human Genome |
| BDM | bill data mediation
| - | Human Genome |
| BD | Blu-ray, An optical disc storage medium. Its main uses are high-definition video and data storage. The disc has the same physical dimensions as standard DVDs or CDs.
| - | Human Genome |
| BE | border edge
| - | Human Genome |
| BECN | backward explicit congestion notification
| - | Human Genome |
| BER | bit error ratio
| - | Human Genome |
| BERT | Bit Error Rate Testing
| - | Human Genome |
| BGAN | Broadband Global Area Network (Inmarsat service)
| - | Human Genome |
| BITS | building integrated timing system
| - | Human Genome |
| BLSR | bidirectional line switched ring
| - | Human Genome |
| BMO | Business Management Office
| - | Human Genome |
| BOC | Bell Operating Company
| - | Human Genome |
| BOD | bandwidth on demand
| - | Human Genome |
| BOE | Body of Evidence
| - | Human Genome |
| BOM | bill of materials
| - | Human Genome |
| BPSR | bidirectional path switched ring
| - | Human Genome |
| BR | basic router
| - | Human Genome |
| BRM | business reference model
| - | Human Genome |
| BS | British standard
| - | Human Genome |
| BSS | Broadcast Satellite Services
| - | Human Genome |
| BT | burst tolerance
| - | Human Genome |
| BW | Digital bandwidth is a rate for data transfer
| - | Human Genome |
