| FAHQT | Fully Automatic High-Quality Translation | - | Human Genome |
| FAMOS | Floating Gate Avalanche MOS | - | Human Genome |
| FAQ | Frequently Asked Questions | - | Human Genome |
| FAT | File Allocation Table | - | Human Genome |
| FBGA | Fine-pitch Ball-grid Array | - | Human Genome |
| FCB | File Control Block | - | Human Genome |
| FCC | File Carbon Copy | - | Human Genome |
| FDD | Floppy Disk Drive | - | Human Genome |
| FDDI | Fiber Distributed Data Interface | - | Human Genome |
| FDHD | Floppy Drive, High Density | - | Human Genome |
| FDM | Frequency Division Multiplexing | - | Human Genome |
| FF | Form Feed | - | Human Genome |
| FFS | Flash File System | - | Human Genome |
| FIF | Fractal Image Format | - | Human Genome |
| FIFO | First In, First Out | - | Human Genome |
| FLOPS | Floating-point Operations Per Second | - | Human Genome |
| FORTRAN | Formula Translator; Programming Language | - | Human Genome |
| FPM RAM | Fast Page Mode RAM | - | Human Genome |
| FPU | Floating-Point Unit | - | Human Genome |
| FR | Frame Relay | - | Human Genome |
| FRAD | Frame Relay Assembler/Disassembler | - | Human Genome |
| FRAM | Ferroelectric RAM | - | Human Genome |
| FSK | Frequency Shift Keying | - | Human Genome |
| FSP | File Service Protocol | - | Human Genome |
| FTP | File Transfer Protocol | - | Human Genome |
| FWIW | For What It's Worth | - | Human Genome |
| FYI | For Your Information | - | Human Genome |
| FAR | Federal Acquisition Regulation
| - | Human Genome |
| FAS | Federal Acquisition Service
| - | Human Genome |
| FASTAR | fast automatic restoration system
| - | Human Genome |
| FAX | Facsimile Transmission. An electronic system capable of scanning documents, converting them to electronic impulses, which are transmitted and received over telephone lines.
| - | Human Genome |
| FB | fixed bandwidth
| - | Human Genome |
| FC | fiber channel
| - | Human Genome |
| FCIA | Fiber Channel Industry Association
| - | Human Genome |
| FCP | fiber channel protocol
| - | Human Genome |
| FDCC | Federal Desktop Core Configuration
| - | Human Genome |
| FDMA | frequency division multiple access
| - | Human Genome |
| FDP | fiber distribution panel
| - | Human Genome |
| FEA | Federal Enterprise Architecture
| - | Human Genome |
| FEC | forward error connection
| - | Human Genome |
| FECN | forward explicit congestion notification
| - | Human Genome |
| FedCIRC | Federal Computer Incident Response Center
| - | Human Genome |
| FED-STD | Federal Standard
| - | Human Genome |
| FFP | firm fixed price
| - | Human Genome |
| FIB | forwarding information base
| - | Human Genome |
| FICON | fiber connectivity
| - | Human Genome |
| FIPS | Federal Information Processing Standard
| - | Human Genome |
| FIRST | Forum of Incident Response and Security Team
| - | Human Genome |
| FISMA | Federal Information Security Management Act
| - | Human Genome |
| Fm-Fm | Find Me Follow Me
| - | Human Genome |
| FO | fail open
| - | Human Genome |
| FOA | firm order acceptance
| - | Human Genome |
| FOC | full operating capability
| - | Human Genome |
| FOCN | firm order commitment notice
| - | Human Genome |
| FODM | fail open detection and mitigation
| - | Human Genome |
| FOIA | Freedom of Information Act
| - | Human Genome |
| FOTS | fiberoptic transport system
| - | Human Genome |
| FPMR | federal property management regulations
| - | Human Genome |
| FRF | frame relay forum
| - | Human Genome |
| FRIP | Functional Requirements Implementation Plan
| - | Human Genome |
| FRS | Frame Relay Services
| - | Human Genome |
| FSDP | fiber service delivery point
| - | Human Genome |
| FSO | free space optics
| - | Human Genome |
| FSS | Fixed Satellite Services
| - | Human Genome |
| FT1 | fractional t1
| - | Human Genome |
| FT3 | fractional t3
| - | Human Genome |
| FTAS | fiber threat analysis system
| - | Human Genome |
| FTR | Federal Telecommunications Recommendations
| - | Human Genome |
| FTS | Federal Technology Service (Federal Telecommunications
| - | Human Genome |
| FTS2001 | Federal Telecommunications System 2001
| - | Human Genome |
| FTTP | fiber to the premises
| - | Human Genome |
| FUSF | Federal Universal Service Fund
| - | Human Genome |
| FWTS | Federal Wireless Telecommunications Service
| - | Human Genome |