| VAR | Value-Added Reseller | - | Human Genome |
| VAX | Virtual Address Extension | - | Human Genome |
| VBE | Vesa Bios Extension | - | Human Genome |
| VBNS | Very High-speed Backbone Network Service | - | Human Genome |
| VCM SDRAM | Virtual-Channel Memory SDRAM | - | Human Genome |
| VCPI | Virtual Control Program Interface | - | Human Genome |
| VCSEL | Vertical-Cavity Surface-Emitting Laser | - | Human Genome |
| VDSL | Very High Bit Rate DSL | - | Human Genome |
| VDT | Video Display Terminal | - | Human Genome |
| VERONICA | Very Easy Rodent-Oriented Networkwide Index To Computerized Archives | - | Human Genome |
| VESA | Video Electronics Standards Association | - | Human Genome |
| VFAT | Virtual File Allocation Table | - | Human Genome |
| VFW | Video For Windows | - | Human Genome |
| VGA | Video Graphics Array (Adapter) | - | Human Genome |
| VLAN | Virtual LAN | - | Human Genome |
| VLB | VESA Local Bus (or VL Bus) | - | Human Genome |
| VME BUS | VersaModule Eurocard Bus | - | Human Genome |
| VMS | Virtual Memory System | - | Human Genome |
| VOB | Voice Over Broadband | - | Human Genome |
| VODSL | Voice Over Digital Subscriber Line | - | Human Genome |
| VOIP | Voice Over Internet Protocol | - | Human Genome |
| VPN | Virtual Private Network | - | Human Genome |
| VR | Virtual Reality | - | Human Genome |
| VRAM | Video Random Access Memory | - | Human Genome |
| VRM | Voltage Regulator Module | - | Human Genome |
| VRML | Virtual Reality Modeling Language | - | Human Genome |
| VRU | Virus Research Unit | - | Human Genome |
| VSA | Virtual Storage Architecture | - | Human Genome |
| VTAM | Virtual Telecommunications Access Method | - | Human Genome |
| VTC | Virus Test Center | - | Human Genome |
| V&H | vertical and horizontal coordinates
| - | Human Genome |
| VAS | value added service
| - | Human Genome |
| VBR | variable bit rate
| - | Human Genome |
| VBR-NRT | variable bit rate-non real time (also known as NRT-VBR)
| - | Human Genome |
| VBR-RT | variable bit rate-real time
| - | Human Genome |
| VC | virtual circuit
| - | Human Genome |
| VCAT | virtual concatenation
| - | Human Genome |
| VCC | virtual channel connections
| - | Human Genome |
| VCO | voice carry over
| - | Human Genome |
| VESDA | very early smoke detection apparatus
| - | Human Genome |
| VFRnrt | variable frame rate-non real time
| - | Human Genome |
| VFRrt | variable frame rate-real time
| - | Human Genome |
| VIF | vertical inlaid fiber
| - | Human Genome |
| VINES | Virtual Integrated Network Service
| - | Human Genome |
| VIP | verification internet protocol
| - | Human Genome |
| VIS | Voice Information System
| - | Human Genome |
| VLDB | very large database
| - | Human Genome |
| VNS | Victim Notification System
| - | Human Genome |
| VoATM | voice over asynchronous transfer mode
| - | Human Genome |
| VOD | video-on-demand
| - | Human Genome |
| VoFR | voice over frame relay
| - | Human Genome |
| VoIPTS | Voice over Internet Protocol Transport Services
| - | Human Genome |
| VPAT | Voluntary Product Accessibility Template
| - | Human Genome |
| VP/VC | virtual path/virtual channel
| - | Human Genome |
| VPIM | voice profile for Internet mail
| - | Human Genome |
| VPLS | Virtual Private Local Area Network Service
| - | Human Genome |
| VPNMon | Virtual Private Network Monitoring
| - | Human Genome |
| VPVN | virtual private voice network
| - | Human Genome |
| VPWS | Virtual Private Wire Service
| - | Human Genome |
| VRF | virtual routing and forwarding
| - | Human Genome |
| VS | Voice Services
| - | Human Genome |
| VSAT | very small aperture terminal
| - | Human Genome |
| VSR | very short reach
| - | Human Genome |
| VSS | Vulnerability Scanning Service
| - | Human Genome |
| VT | virtual tributary
| - | Human Genome |
| VT1.5 | Virtual Tributary 1.5
| - | Human Genome |
| VTS | Video Teleconferencing Services
| - | Human Genome |
| VTU | Video Terminal Unit
| - | Human Genome |
| VXML | voice eXtensible markup language
| - | Human Genome |