| MAE | Metropolitan Area Exchange (Ethernet) | - | Human Genome |
| MAN | Metropolitan Area Network | - | Human Genome |
| MAPI | Messaging Application Programming Interface | - | Human Genome |
| MARS | Multi-player Animated Role-playing System | - | Human Genome |
| MATHML | Mathematical Markup Language | - | Human Genome |
| MAU | Media Access Unit | - | Human Genome |
| MAU | Multistation Access Unit | - | Human Genome |
| MB | Megabit | - | Human Genome |
| MB | Megabyte | - | Human Genome |
| MBPS | Megabits Per Second | - | Human Genome |
| MBR | Master Boot Record | - | Human Genome |
| MCA | Micro Channel Architecture | - | Human Genome |
| MCGA | Multi-Color Graphics Array | - | Human Genome |
| MCI | Media Control Interface | - | Human Genome |
| MDA | Monochrome Display Adapter | - | Human Genome |
| MDC | Metadata Coalition | - | Human Genome |
| MDI | Multiple Document Interface | - | Human Genome |
| MDIS | Metadata Interchange Specification | - | Human Genome |
| MEMS | MicroElectro-Mechanical System | - | Human Genome |
| MFLOPS | Millions Of Floating Point Operations Per Second | - | Human Genome |
| MFM | Modified Frequency Modulation | - | Human Genome |
| MIB | Management Information Base | - | Human Genome |
| MICR | Magnetic Ink Character Recognition (Reader) | - | Human Genome |
| MIDI | Musical Instrument Digital Interface | - | Human Genome |
| MIF | Management Information Format | - | Human Genome |
| MILNET | Military Network | - | Human Genome |
| MIME | Multipurpose Internet Mail Extension | - | Human Genome |
| MIPS | Millions Of Instructions Per Second | - | Human Genome |
| MIS | Management Information System | - | Human Genome |
| MIS | Management Information Services | - | Human Genome |
| MLC | Multilevel Cell | - | Human Genome |
| MMDS | Multichannel Multipoint Distribution System | - | Human Genome |
| MMU | Memory Management Unit | - | Human Genome |
| MMX | Matrix Math Extensions (Multimedia Extensions) | - | Human Genome |
| MNG | Multiple-image Network Graphics | - | Human Genome |
| MNP | Microcom Networking Protocol | - | Human Genome |
| MODEM | Modulator/Demodulator | - | Human Genome |
| MOF | Meta Object Facility | - | Human Genome |
| MOO | Mud, Object Oriented | - | Human Genome |
| MOS | Metal Oxide Semiconductor | - | Human Genome |
| MOSFET | Metal Oxide Semiconductor Field Effect Transistor | - | Human Genome |
| MOSIS | MOS Implementation System | - | Human Genome |
| MOSS | Mime Object Security Services | - | Human Genome |
| MP3 | MPEG Layer 3 | - | Human Genome |
| MPC | Matchbox PC | - | Human Genome |
| MPC | Multimedia Personal Computer | - | Human Genome |
| MPEG | Motion Picture Experts Group | - | Human Genome |
| MPI | Message Passing Interface | - | Human Genome |
| MRC | Magneto-Resistive Cluster | - | Human Genome |
| MS-DOS | Microsoft Disk Operating System | - | Human Genome |
| MSN | Microsoft Network | - | Human Genome |
| MTA | Media Terminal Adapter | - | Human Genome |
| MTBF | Mean Time Between Failure | - | Human Genome |
| MTU | Maximum Transmission Unit | - | Human Genome |
| MUD | Multiple User (or Multi-User) Dungeon (Dimension) | - | Human Genome |
| MUSH | Multi-User Shared Hallucination | - | Human Genome |
| MVS | Multiple Virtual Storage | - | Human Genome |
| MAA | Metropolitan Area Acquisition
| - | Human Genome |
| MAC | mandatory access control
| - | Human Genome |
| M/A/C | move/add/change
| - | Human Genome |
| MAP | mobile application part
| - | Human Genome |
| MAR | maximum allocation resource
| - | Human Genome |
| MARC | multi-Agency radio communications
| - | Human Genome |
| MARO | Managed Internet Service Access Redundancy Options
| - | Human Genome |
| MARO-BNR | Managed Internet Service Access Redundancy Options- Backbone Node Redundancy
| - | Human Genome |
| MAS | messaging applications server
| - | Human Genome |
| MBS | maximum burst size
| - | Human Genome |
| MCB | management control bridge
| - | Human Genome |
| MCC | migration control center
| - | Human Genome |
| MCR | minimum cell rate
| - | Human Genome |
| MCS | mobile switching center
| - | Human Genome |
| MCSE | Microsoft Certified Systems Engineer
| - | Human Genome |
| MCU | multipoint control unit
| - | Human Genome |
| MEAS | Managed E-Authentication Service
| - | Human Genome |
| MEF | Metro Ethernet Forum
| - | Human Genome |
| MEGACO | media gateway control
| - | Human Genome |
| MEN | metro Ethernet network
| - | Human Genome |
| MF | multifrequency
| - | Human Genome |
| MFAB | major failure action binder
| - | Human Genome |
| MFI | multifunction interpreter
| - | Human Genome |
| MFS | Managed Firewall Service
| - | Human Genome |
| MGCP | media gateway control protocol
| - | Human Genome |
| MIDS | Managed Intrusion Detection Service
| - | Human Genome |
| MIP | Major Incident Plan
| - | Human Genome |
| MITT | Medical Information Technology Transition
| - | Human Genome |
| MLPP | multilevel precedence and pre-emption
| - | Human Genome |
| MMC | multimedia commands
| - | Human Genome |
| MMP | Migration Management Plan
| - | Human Genome |
| MMRC | maintenance monthly recurring cost
| - | Human Genome |
| MMS | Multimedia Messaging Service
| - | Human Genome |
| MNS | Managed Network Services
| - | Human Genome |
| MOPS | management and operations
| - | Human Genome |
| MOU | minutes of use
| - | Human Genome |
| MP-iBGP | multiprotocol internal border gateway protocol
| - | Human Genome |
| MPIN | Marketing Partner Identification Number
| - | Human Genome |
| MPLS | multiprotocol label switching
| - | Human Genome |
| MPOP | minimum point of penetration
| - | Human Genome |
| MRG | minimum revenue guarantee
| - | Human Genome |
| MS | media server
| - | Human Genome |
| MS-SQL | Microsoft-Structured Query Language
| - | Human Genome |