| L2TP | Layer Two Tunneling Protocol | - | Human Genome |
| LAN | Local Area Network | - | Human Genome |
| LAWN | Local-Area Wireless Network | - | Human Genome |
| LBA | Logical Block Addressing | - | Human Genome |
| LBV | Layered Biometric Verification | - | Human Genome |
| LCD | Liquid-Crystal Display | - | Human Genome |
| LDAP | Lightweight Directory Access Protocol | - | Human Genome |
| LED | Light Emitting Diode | - | Human Genome |
| LEP | Light Emitting Polymers | - | Human Genome |
| LGMR | Laser Guided Magnetic Recording | - | Human Genome |
| LI-ION | Lithium Ion | - | Human Genome |
| LIFO | Last In, First Out | - | Human Genome |
| LILO | Linux Loader | - | Human Genome |
| LIM | Lifeline Interface Module | - | Human Genome |
| LIM | Lotus-Intel-Microsoft | - | Human Genome |
| LMB | Left Mouse Button | - | Human Genome |
| LPM | Lifeline Port Module | - | Human Genome |
| LPM | Lines Per Minute | - | Human Genome |
| LPT | Local Printer Terminal | - | Human Genome |
| LTO | Linear Tape Open | - | Human Genome |
| LZW | Lempel-Zif-Welsh | - | Human Genome |
| L2VPNS | Layer 2 Virtual Private Network Services
| - | Human Genome |
| LAP | link access protocol
| - | Human Genome |
| LAPB | link access protocol basic for X.25
| - | Human Genome |
| LAPD | link access protocol for D channel signaling (ISDN)
| - | Human Genome |
| LATA | local access and transport area
| - | Human Genome |
| LBR | low-bit rate
| - | Human Genome |
| LC-CELP | low complexity - code excited linear predictive
| - | Human Genome |
| LCAS | link capacity adjustment scheme
| - | Human Genome |
| LDIF | lightweight directory access protocol data interchange format
| - | Human Genome |
| LDP | label distribution protocol
| - | Human Genome |
| LEC | local exchange carrier
| - | Human Genome |
| LEO | low earth orbit
| - | Human Genome |
| LERG | local exchange routing guide
| - | Human Genome |
| LFD | large file download
| - | Human Genome |
| LGC | local government contact
| - | Human Genome |
| LH | long haul
| - | Human Genome |
| LLDS | Link Layer Data Service
| - | Human Genome |
| LMDS | Local Multipoint Distribution System
| - | Human Genome |
| LMR | land mobile radio
| - | Human Genome |
| LMRAS | Land Mobile Radio Access Services
| - | Human Genome |
| LMRS | Land Mobile Radio Services
| - | Human Genome |
| LND | last number dialed
| - | Human Genome |
| LNP | local number portability
| - | Human Genome |
| LNS | local network service
| - | Human Genome |
| LOH | line overhead
| - | Human Genome |
| LONESTAR | local network services technology recovery
| - | Human Genome |
| LPR | local primary reference
| - | Human Genome |
| LR | long reach
| - | Human Genome |
| LR1-SLM | long reach – single – longitudinal mode
| - | Human Genome |
| LSMR | local span mesh restoration
| - | Human Genome |
| LSO | local serving offices
| - | Human Genome |
| LSP | label switch path
| - | Human Genome |
| LWS | Lucent Worldwide Services
| - | Human Genome |
