| I/O | Input/Output | - | Human Genome |
| IAB | Internet Architecture Board | - | Human Genome |
| IAC | Internet Access Coalition | - | Human Genome |
| IAD | Integrated Access Device | - | Human Genome |
| IAHC | Internet International Ad Hoc Committee | - | Human Genome |
| IANA | Internet Assigned Numbers Authority | - | Human Genome |
| IANAL | I Am Not A Lawyer | - | Human Genome |
| IAS | Internet Authentication Service | - | Human Genome |
| IBM | International Business Machines | - | Human Genome |
| ICA | Independent Computing Architecture | - | Human Genome |
| ICANN | The Internet Corporation For Assigned Names And Numbers | - | Human Genome |
| ICMP | Internet Control Message Protocol | - | Human Genome |
| IDE | Intelligent (Integrated) Drive Electronics | - | Human Genome |
| IDEA | International Data Encryption Algorithm | - | Human Genome |
| IDSL | ISDN Digital Subscriber Line | - | Human Genome |
| IEEE | Institute Of Electrical And Electronics Engineers | - | Human Genome |
| IETF | Internet Engineering Task Force | - | Human Genome |
| IGES | Initial Graphics Exchange Specification | - | Human Genome |
| IGMP | Internet Group Management Protocol | - | Human Genome |
| IIM | Internet Interaction Management | - | Human Genome |
| IIOP | Internet Inter-ORB Protocol | - | Human Genome |
| IIS | Internet Information Server | - | Human Genome |
| IMAP | Internet Message Access Protocol | - | Human Genome |
| IMHO | In My Humble Opinion | - | Human Genome |
| INTERNIC | Internet Network Information Center | - | Human Genome |
| IOS | Input Output System | - | Human Genome |
| IP | Internet Protocol | - | Human Genome |
| IPSEC | Internet Protocol Security | - | Human Genome |
| IPTV | Internet Protocol Television | - | Human Genome |
| IPX | Internetwork Packet Exchange | - | Human Genome |
| IRC | Internet Relay Chat | - | Human Genome |
| IRDA | Infrared Data Association | - | Human Genome |
| IRQ | Interrupt Request | - | Human Genome |
| ISA | Industry Standard Architecture | - | Human Genome |
| ISAM | Indexed Sequential Access Method | - | Human Genome |
| ISAPI | Internet Server API | - | Human Genome |
| ISDN | Integrated Services Digital Network | - | Human Genome |
| ISO | International Organization For Standardization | - | Human Genome |
| ISP | Internet Service Provider | - | Human Genome |
| ITU | International Telecommunications Union | - | Human Genome |
| IX | Internet Exchange | - | Human Genome |
| IA | Information Assurance
| - | Human Genome |
| IAM | initial address message
| - | Human Genome |
| IA/RA | Interactive Announcement/Response Arrangement
| - | Human Genome |
| IATO/IATT | Interim Authority to Operation/Test
| - | Human Genome |
| IC | integration contractor
| - | Human Genome |
| ICB | individual case basis
| - | Human Genome |
| ICC | Implementation Control Center
| - | Human Genome |
| ICI | inter carrier interface
| - | Human Genome |
| ICM | Intelligent Contact Management (Cisco)
| - | Human Genome |
| ICP | intelligent call processing
| - | Human Genome |
| ICT | Information and Communication Technology
| - | Human Genome |
| ID | identification (user)
| - | Human Genome |
| IDC | Internet Data Center
| - | Human Genome |
| IDIQ | indefinite delivery, indefinite quantity
| - | Human Genome |
| IDLH | immediately dangerous to life or health
| - | Human Genome |
| i-DNS | Intelligent-Delivery Network Services
| - | Human Genome |
| IDPS | Intrusion Detection and Prevention Service
| - | Human Genome |
| IDS | intrusion detection systems
| - | Human Genome |
| IEC | International Electrotechnical Commission
| - | Human Genome |
| IEMS | International Emergency Multimedia Service
| - | Human Genome |
| IFS | Internet Facsimile Service
| - | Human Genome |
| iGEMS | Integrated Global Enterprise Management System
| - | Human Genome |
| IGRP | interior gateway routing protocol
| - | Human Genome |
| IIF | interworking and interoperability function
| - | Human Genome |
| ILEC | incumbent local exchange carrier
| - | Human Genome |
| IMA | inverse multiplexing over ATM
| - | Human Genome |
| IMC | Interagency Management Council
| - | Human Genome |
| IMP | Implementation Management Plan
| - | Human Genome |
| IMS | Internet protocol multimedia subsystem
| - | Human Genome |
| IMSI | International Mobile Subscriber Identity
| - | Human Genome |
| IMT | international mobile telecommunications
| - | Human Genome |
| INC | international carrier
| - | Human Genome |
| INCITS | International Committee for Information Technology Standards
| - | Human Genome |
| INMARSAT | International Maritime Satellite Organization
| - | Human Genome |
| INRS | Incident Response Service
| - | Human Genome |
| INSTAR | IP Network Systems and Asset Resource
| - | Human Genome |
| INT | integer function
| - | Human Genome |
| IOC | inter-office channel
| - | Human Genome |
| IOM | integrated order manager
| - | Human Genome |
| IOPS | input/output per second
| - | Human Genome |
| IPA | identity proofing agent
| - | Human Genome |
| IPBE | Internet protocol border element
| - | Human Genome |
| IPeFR | Internet protocol-enabled frame relay
| - | Human Genome |
| IPL | international private line
| - | Human Genome |
| IPM | interpersonal messaging
| - | Human Genome |
| IPPM | Internet Protocol (IP) Protocol Network
| - | Human Genome |
| IPS | Internet protocol service
| - | Human Genome |
| IPT | Integrated Product Team
| - | Human Genome |
| IPTelS | IP Telephony Service
| - | Human Genome |
| IP-VPNS | Internet Protocol-Virtual Private Network Service
| - | Human Genome |
| IPVTS | Internet Protocol Video Transport Services
| - | Human Genome |
| IR1-SLM | intermediate reach – single – longitudinal mode
| - | Human Genome |
| IRAS | integrated routing assignment system
| - | Human Genome |
| I.R.C. | Internal Revenue Code
| - | Human Genome |
| IRFC | Internet route free core
| - | Human Genome |
| IRP | Incident Response Plan
| - | Human Genome |
| IRS | Internal Revenue Service
| - | Human Genome |
| IRU | indefeasible rights of use
| - | Human Genome |
| IS-41 | North American Standard for Wireless TelecommunicationsNetwork Signaling
| - | Human Genome |
