| HAL | Hardware Abstraction Layer | - | Human Genome |
| HD | High Density | - | Human Genome |
| HD | Hard Drive | - | Human Genome |
| HDD | Hard Disk Drive | - | Human Genome |
| HDLC | High-level Data Link Control | - | Human Genome |
| HDML | Handheld Device Markup Language | - | Human Genome |
| HDR | High Data Rate | - | Human Genome |
| HDTV | High-Definition Television | - | Human Genome |
| HFS | Hierarchical Filing System | - | Human Genome |
| HMA | High Memory Area | - | Human Genome |
| HMD | Head-Mounted Display | - | Human Genome |
| HP | Hewlett-Packard | - | Human Genome |
| HP-GL | Hewlett-Packard Graphics Language | - | Human Genome |
| HPAS | Hypermedia Presentation And Authoring System | - | Human Genome |
| HPFS | High Performance File System | - | Human Genome |
| HSL | Hypermedia Synchronization Language | - | Human Genome |
| HSM | Hierarchical Storage Management | - | Human Genome |
| HTML | Hypertext Markup Language | - | Human Genome |
| HTTP | Hypertext Transfer Protocol | - | Human Genome |
| HTTPD | Hypertext Transfer Protocol Daemon (Server) | - | Human Genome |
| H-VPLS | hierarchical VPLS
| - | Human Genome |
| HazMat | hazardous materials
| - | Human Genome |
| HAZWOPER | Hazardous Waste Operations and Emergency Response
| - | Human Genome |
| HBA | host bus adapter
| - | Human Genome |
| HCO | hearing carry over
| - | Human Genome |
| HDPE | high-density polyethylene
| - | Human Genome |
| HF | high frequency
| - | Human Genome |
| HID | host intrusion detection
| - | Human Genome |
| HITS | Hawaii Information Transfer System
| - | Human Genome |
| HLR | home location register
| - | Human Genome |
| HPC | high probability of completion
| - | Human Genome |
| HPPI | high performance parallel interface
| - | Human Genome |
| HR | human resources
| - | Human Genome |
| HSD | high-speed data
| - | Human Genome |
| HSDPA | high-speed downlink packet access
| - | Human Genome |
| HSPS | High-Speed Packet Services
| - | Human Genome |
| HSSI | high speed serial interface
| - | Human Genome |
| HVAC | heating, ventilation, and air conditioning
| - | Human Genome |
| HIP | Horizon Internet Protocol; The V-Cat database on the Internet.
| - | Human Genome |
