| GBE | Gigabit Ethernet | - | Human Genome |
| GDI | Graphics Device Interface | - | Human Genome |
| GIF | Graphical Interchange Format | - | Human Genome |
| GIGO | Garbage In, Garbage Out | - | Human Genome |
| GIMP | General (GNU) Image Manipulation Program | - | Human Genome |
| GIS | Geographic Information System | - | Human Genome |
| GM | General MIDI | - | Human Genome |
| GMT | Greenwich Mean Time | - | Human Genome |
| GNU | Recursive Acronym For ?GNU's Not Unix? | - | Human Genome |
| GPF | General Protection Fault | - | Human Genome |
| GPRS | General Packet Radio Service | - | Human Genome |
| GPS | Global Positioning Satellite (System) | - | Human Genome |
| GREP | Globally Search For The Regular Expression And Print | - | Human Genome |
| GREP | Generalized Regular Expression Pattern-matcher | - | Human Genome |
| GRINS | Graphical Interface To SMIL | - | Human Genome |
| GSM | Global System For Mobiles | - | Human Genome |
| GUI | Graphical User Interface | - | Human Genome |
| GUID | Globally Unique Identifier | - | Human Genome |
| GAM | global account manager
| - | Human Genome |
| GAMnet | global account management network
| - | Human Genome |
| GAO | General Accounting Office
| - | Human Genome |
| Gbps | Gigabit per second
| - | Human Genome |
| Gbyte | Gigabyte
| - | Human Genome |
| GCL | Government Communications Laboratory
| - | Human Genome |
| GCRA | generic cell rate algorithm
| - | Human Genome |
| GCSC | Global Customer Support Center
| - | Human Genome |
| GEICO | Government Employees Insurance Company
| - | Human Genome |
| GETN | Government Education & Training Network
| - | Human Genome |
| GETS | Government Emergency Telecommunications Service
| - | Human Genome |
| GFE | Government furnished equipment
| - | Human Genome |
| GFMS | global fraud management system
| - | Human Genome |
| GFP | Government furnished property (formerly Government furnished equipment)
| - | Human Genome |
| GGSN | gateway general support node
| - | Human Genome |
| GHz | Gigahertz
| - | Human Genome |
| GIAC | Global Information Assurance Certification
| - | Human Genome |
| GIDC | global internet data center
| - | Human Genome |
| GigE | Gigabit Ethernet
| - | Human Genome |
| GIGR | Gigabit Internet gateway router
| - | Human Genome |
| GMIS | government managed internet service
| - | Human Genome |
| GMPLS | generalized multiprotocol label switching
| - | Human Genome |
| GMS | Government Management Service
| - | Human Genome |
| GNOC | Global Network Operations Center
| - | Human Genome |
| GoS | grade of service
| - | Human Genome |
| GOTS | Government-Off-The-Shelf
| - | Human Genome |
| GPMP | General Project Management Plan
| - | Human Genome |
| GQ | generational qualifier
| - | Human Genome |
| GRE | general routing encapsulation protocol
| - | Human Genome |
| GRL | Global Response Loop
| - | Human Genome |
| GSA | General Services Administration
| - | Human Genome |
| GSAM | GSA Acquisition Manual
| - | Human Genome |
| GSAR | GSA Regulation
| - | Human Genome |
| GSII | Government Services Information Infrastructure
| - | Human Genome |
| GSR | Global Servicing Router
| - | Human Genome |
| GSS | AT&T Global Strategic Sourcing
| - | Human Genome |
| GTCOMM | globally transportable satellite packages
| - | Human Genome |
| GVTP | General Verification Test Plan
| - | Human Genome |
